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Surgical management of secondary hyperparathyroidism in chronic kidney disease—a consensus report of the European Society of Endocrine Surgeons

机译:慢性肾脏疾病继发性甲状旁腺功能亢进症的外科治疗-欧洲内分泌外科医师学会的共识报告

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摘要

Despite advances in the medical management of secondary hyperparathyroidism due to chronic renal failure and dialysis (renal hyperparathyroidism), parathyroid surgery remains an important treatment option in the spectrum of the disease. Patients with severe and complicated renal hyperparathyroidism (HPT), refractory or intolerant to medical therapy and patients with specific requirements in prospect of or excluded from renal transplantation may require parathyroidectomy for renal hyperparathyroidism. METHODS: Present standard and actual controversial issues regarding surgical treatment of patients with hyperparathyroidism due to chronic renal failure were identified, and pertinent literature was searched and reviewed. Whenever applicable, evaluation of the level of evidence concerning diagnosis and management of renal hyperparathyroidism according to standard criteria and recommendation grading were employed. Results were discussed at the 6th Workshop of the European Society of Endocrine Surgeons entitled Hyperparathyroidism due to multiple gland disease: An evidence-based perspective.
机译:尽管由于慢性肾功能衰竭和透析引起的继发性甲状旁腺功能亢进症的医疗管理取得了进展,但甲状旁腺手术仍然是该病范围内的重要治疗选择。患有严重和复杂的肾脏过度甲状旁腺功能亢进症(HPT),难治性或不耐受药物治疗的患者以及对有可能接受肾脏移植或被排除在肾脏移植之外有特殊要求的患者,可能需要进行甲状旁腺切除术治疗肾脏过度甲状旁腺功能亢进。方法:确定目前有关慢性肾功能衰竭甲状旁腺功能亢进症手术治疗的标准和实际争议性问题,并检索和复习相关文献。只要适用,就应根据标准标准和推荐等级对有关肾功能亢进的诊断和治疗的证据水平进行评估。结果在欧洲内分泌外科医师学会第六次研讨会上进行了讨论,该研讨会的标题为“由于多腺体疾病引起的甲状旁腺功能亢进:基于证据的观点”。

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